| Name | Position | Year |
| Amb. Macharia Kamau,CBS | Principal Secretary for Foreign Affairs | Feb 2018 – Dec 2022 |
| Amb. Dr. Monica Juma | Principal Secretary for Foreign Affairs | 2015-2018 |
| Dr. Eng. Karanja Kibicho | Principal Secretary for Foreign Affairs | 2013-2015 |
| Mr. Thuita Mwangi | Permanent Secretary for Foreign Affairs | 2006 -2013 |
| Amb. Boaz Kadiga Mbaya | Permanent Secretary for Foreign Affairs | 2005 |
| Amb. Esther Tolle | Permanent Secretary for Foreign Affairs | 2004 |
| Amb. Peter O. Ole Nkuraiya | Permanent Secretary for Foreign Affairs | 2003 |
| Rebecca Nabutola | Permanent Secretary for Foreign Affairs | 2002 |
| David Andere | Permanent Secretary for Foreign Affairs | 2001 |
| Dr. Sally Kosgei | Permanent Secretary for Foreign Affairs | 1992 -2001 |
| Amb. Bethuel Kiplagat | Permanent Secretary for Foreign Affairs | 1985 |
| Japheth G. Shamalla | Permanent Secretary for Foreign Affairs | 1981 |
| Joseph Muchemi | Permanent Secretary for Foreign Affairs | 1980 |
| Joseph Muliro | Permanent Secretary for Foreign Affairs | 1979 |
| Nicholas Ng’ang’a | Permanent Secretary for Foreign Affairs | 1978 |
| Leonard Kibinge | Permanent Secretary for Foreign Affairs | 1974 |
| George Matheka | Permanent Secretary for Foreign Affairs | 1971 |
| Dawson Mlamba | Permanent Secretary for Foreign Affairs | 1970 |
| John Kyalo | Permanent Secretary for Foreign Affairs | 1967-1970 |
| T. C. J. Ramtu | Permanent Secretary for Foreign Affairs | 1964 |
| Dr. Robert J. Ouko | Permanent Secretary for Foreign Affairs | 1963 |